A few things:
1. It's rare to need so many connections. Start with a small number (5-10) and test your speed. Always use the minimum number of connections to get the maximum speed.
2. Check with your NSP about any server or routing problems on their side.
3. Check your ISP about any potential throttling or network congestion.
4. Disable NNTP checking with Avast - or completely uninstall it and use MSE instead.
And please anonymize any posted images.